RINDERVAX TM

Live Attenuated Rinderpest Virus Vaccine

COMPOSITION

RINDERVAX TM is a freeze-dried live attenuated Rinderpest virus vaccine prepared from the Kabete ‘O’ strain of the virus. The diluent is used to re-hydrate the freeze-dried component.

PROPERTIES

Rinderpest is an acute, fatal disease of domestic cattle and buffalo caused by a mobillivirus in the family Paramyxoviridae. The virus also affects sheep, goats and Asiatic pigs and a large variety of free-living species within the order Artiodactyla, although not always in a clinically apparent form.

Clinically, the disease is characterised by pyrexia, the progressive development of shallow erosions on the gums, tongue, cheeks, and hard palate, together with serous or mucopurulent ocular and nasal discharges. Alimentary tract involvement is marked by the development of severe diarrhoea.

RINDERVAX TM was developed at the former East African Veterinary Research Organisation (now KEVEVAPI) by serial passage of the virulent bovine rinderpest strain kabete ‘O’. It is safe for use in cattle, buffalo, sheep and goats of all ages.

INDICATIONS

For the active immunisation of healthy cattle against Rinderpest.

DOSAGE AND ADMINISTRATION

Reconstitute each vial with the corresponding sterile diluent. Keep the reconstituted vaccine cool and protected from sunlight. Take reasonable aseptic precautions in reconstituting and withdrawing the vaccine. Administer via the subcutaneous route to animals of at least 6 months of age at the rate of 2ml per animal.

The resulting immunity is lifelong and therefore animals should be vaccinated only once in a lifetime.

CONTRA-INDICATIONS, WARNINGS

For Veterinary use only. Do not use if seal is broken or package is damaged.

Do not vaccinate un-healthy animals.

All vaccines may occasionally cause anaphylactic reactions in some animals. If this occurs adrenaline should be administered.

STORAGE

Store at -200C. (Freezer). Under these conditions, the shelf life is 2 years.

If stored at between +20C and +80 C (refrigerator) the shelf life is one month.

Once the vaccine has been reconstituted, it must be used immediately ( within 2 hours if chilled or within 1 hour in case not chilled) and any remaining quantity discarded.

PRESENTATION

50-, and 100-dose vials packed together with the corresponding diluent.