Fibronectin(FN1/2949) , CF488A conjugate , 0.1mg / mL

Fibronectins are disulfide-linked , dimeric glycoproteins of ~440 kDa. They possess at least four binding sites for collagen , glycosaminoglycans , transglutaminase , and a cell surface receptor. Epitope of this MAb is located in the 2nd-3rd type-III repeats of fibronectin. Fibronectins are extracellular matrix glycoproteins that are essential for embryonic development. Fibronectins are also involved in cell adhesion , tissue organization , and wound healing. Fibronectins are present in basement membranes , interstitial connective tissue matrix , and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb reacts with human cellular fibronectin , but not plasma fibronectin. Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.