ALOX12 Antibody HRP conjugated

Volume : 50 µg
Clone Number :
Aliases : 12 LOX antibody; 12(S) lipoxygenase antibody; 12-lipoxygenase antibody; 12LO antibody; 12S LOX antibody; 12S-lipoxygenase antibody; 12S-LOX antibody; 12S-type antibody; Alox12 antibody; Arachidonate 12 lipoxygenase antibody; Arachidonate 12 lipoxygenase, 12S type antibody; Arachidonate 12-lipoxygenase antibody; Arachidonate 12-oxidoreductase antibody; Lipoxin synthase 12-LO antibody; LOG12 antibody; LOX12_HUMAN antibody; P-12LO antibody; Platelet 12-LOX antibody; Platelet type lipoxygenase 12 antibody; platelet-type 12-lipoxygenase antibody; Platelet-type lipoxygenase 12 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P18054
Immunogen : Recombinant Human Arachidonate 12-lipoxygenase, 12S-type protein (508-658AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE but can also metabolize linoleic acid. Has a dual activity since it also converts leukotriene A4/LTA4 into both the bioactive lipoxin A4/LXA4 and lipoxin B4/LXB4. Thro µgh the production of specific bioactive lipids like (12S)-HPETE it reg µLates different biological processes including platelet activation. It also probably positively reg µLates angiogenesis thro µgh reg µLation of the expression of the vasc µLar endothelial growth factor. Plays a role in apoptotic process, promoting the survival of vasc µLar smooth muscle cells for instance. May also play a role in the control of cell migration and proliferation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ALOX12
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction