FZD9 Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : CD 349 antibody; CD 349 antigen antibody; CD349 antibody; Frizzled Drosophila homolog of 3 antibody; Frizzled homolog 9 (Drosophila) antibody; Frizzled homolog 9 antibody; Frizzled-9 antibody; Fz 9 antibody; Fz-9 antibody; FZD 3 antibody; Fzd 9 antibody; FZD3 antibody; FZD3-PEN antibody; FZD9 antibody; FZD9_HUMAN antibody; FzE6 antibody; hFz9 antibody; mfz9 antibody; Xfz9 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00144
Immunogen : Recombinant Human Frizzled-9 protein (23-229AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accum µLation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercell µLar transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FZD9
Research Areas : Neuroscience; Stem cells